Endocrine Abstracts

Most endocrinologists are aware of biological rhythms. As undergraduates, we might learn about the menstrual cycle in humans, seasonal changes in reproductive physiology in many animal species, and the circadian and ultradian patterns of cortisol secretion. In recent decades, research has started to uncover the full scope of the circadian clock’s influence on physiology (and pathophysiology). It is increasingly clear that we need to account for this in experimental design. In this workshop, I...

Background: Bone marrow transplant (BMT) survivors are at increased risk of metabolic syndrome and developing type 2 diabetes (T2DM). Measurement of HbA1c is increasingly used in recent years for the diagnosis of T2DM. An HbA1c level of ≥6.5% (48 mmol/mol) is considered as a diagnostic cut-off for T2DM and an HbA1c between 6.0–6.4% (42–47 mmol/mol) is considered as at risk of T2DM. We aimed to look at the diagnostic performance of HbA1c and oral glucose toleran...